Anthropic · Claude · Microsoft · The Verge
Claude Fable clinched’t answer basic biology questions
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To protect against bioweapons, Anthropic told The Verge Fable’s ‘overly conservative’ safeguards block ‘most queries tied to biology work.’.
Key facts
- Instead, it hands off the query to the former flagship model, Claude Opus 4.8
- Anthropic released Claude Fable 5, calling it the most powerful AI model it has ever made widely available and praising its skills in biology, among others
- To protect against bioweapons, Anthropic told The Verge Fable’s ‘overly conservative’ safeguards block ‘most queries tied to biology work
- Some of their basic queries occasionally got through, with Fable answering questions like “what is cancer” and “what is DNA
Summary
Anthropic released Claude Fable 5, calling it the most powerful AI model it has ever made widely available and praising its skills in biology, among others. Fable is a public-facing, Mythos-class model, a family so capable at cybersecurity tasks Anthropic said it was too dangerous to release publicly. When the reporter tried the model, it refused to answer a range of basic biology questions, many that felt about as far away from any plausible safety risk as any question could be. “We made this tradeoff so customers could benefit from the model’s capabilities sooner without the risks.”