Tech · MIT Technology Review
Scientists just assembled female clones of male mice
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◌ Single Source
Scientists have deliberately turned male mouse embryos into females for the first time.
Key facts
- In 2009, researchers reported the accidental birth of a single female pup in a batch of 27 clones created from male mouse cells
- In 2023, Katsuhiko Hayashi of Osaka University and his colleagues showed they could turn cells taken from male mice into egg cells
- No one has done this before,” says Monika Ward, a reproductive biologist at the University of Hawaii, who was not involved in the research
- The feat could change the way scientists think about reproduction, says Takashi Ishiuchi, a reproductive biologist at the University of Yamanashi, who co-led the work
Summary
“No one has done this before,” says Monika Ward, a reproductive biologist at the University of Hawaii, who was not involved in the research. The feat could change the way scientists think about reproduction, says Takashi Ishiuchi, a reproductive biologist at the University of Yamanashi, who co-led the work. He and his colleague Shogo Matoba of the Riken BioResource Research Center in Ibaraki also hope their technique could help rescue endangered species, particularly in cases where only a few individuals remain. “It’s exciting to see,” says Ben Novak, lead scientist at the wildlife conservation organization Revive & Restore, who was not involved in the work.