Funding Round · Crunchbase News
The Week’s 10 Biggest Funding Rounds: AI, Energy And Biotech Lead The Way
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This is a weekly feature that runs down the week’s top 10 announced funding rounds in the U.S. Check out last week’s biggest funding deal roundup here.
Key facts
- 6. (tied) Twelve Labs, $100M, video-based AI: Twelve Labs, a San Francisco-based startup developing AI systems trained on video archives, raised $100 million in a Series B round co-led by New
- 6. (tied) Premier Lacrosse League, $100 million, professional sports: The Premier Lacrosse League, a men’s professional lacrosse league in North America, closed a $100 million Series E financing
- 4. 8090 Solutions, $135M, AI software development: Redwood City, California-based 8090 Solutions, developer of a platform for building enterprise software with coordinated AI agents under human-led
- Beeline Medicines, $126M, biotech: Boston-based Beeline Medicines, a startup focused on precision therapies for autoimmune and inflammatory diseases, secured $126 million in Series A extension
Summary
Want to keep track of the largest startup funding deals in 2026 with their curated list of $100 million-plus venture deals to U.S.-based companies? U.S. startups announced sizable funding rounds at a steady clip during a truncated holiday week, with energy and AI leading the way. Houston-based energy startup Joulent secured the biggest round, a $1.75 billion strategic financing, followed by Together AI, a developer of infrastructure for companies running open source AI models, and LeapXpert, a provider of compliance tools for enterprises. Other big rounds were for companies focused on therapeutics, homebuilding, and even lacrosse.