Google · The Atlantic Technology
DiNardo claimed that Mindstate’s AI works like AlphaFold, the model from Google DeepMind that has wowed structural biologists—and
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Nature is always performing chemistry experiments, and in the dark and sticky corners of its forests and jungles, it creates compounds that have hyper-specific effects on the human mind.
Key facts
- A psilocybin analogue developed by Reunion Neuroscience appears to produce a high that lasts three or four hours, according to findings from a Phase 2 trial of 84 women with postpartum depression
- For 17 centuries, Chinese Taoists have been preserving one such text called Baopuzi
- People who use psilocybin recreationally may become confused and jump off a building, David Yaden, a researcher at the Center for Psychedelic and Consciousness Research at Johns Hopkins University
- Mindstate started by compiling a large database of more than 70,000 trip reports
Summary
In China’s Yunnan province, a yellow mushroom with a droopy cap sprouts up in the mountains, usually in the shade of long-needled pines. Many people of different ages and cultural backgrounds have eaten this mushroom and experienced the same hallucination. For thousands of years, humans have searched nature for mind-altering substances through a process of trial and (sometimes fatal) error. Now that psychedelic research has been legitimized, scientists at university labs and biotech start-ups are wondering whether they can create a better one. “Nature’s compounds aren’t always optimal,” Manoj Doss, a professor of psychiatry at the University of Texas at Austin, told me. A single dose of it seems to help people liberate themselves from opioids, quelling their cravings and mellowing their withdrawal symptoms.