NIST · NIST AI
NISTCHO: Monoclonal Antibody Producing Cell Line
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★ Tier-1 Source
A reference material for biomanufacturing innovation and collaboration.
Key facts
- NISTCHO was originally released as RM 10197 from January 2023 until October 2024
- NISTCHO expands the biomanufacturing and research applications of highly-successful NIST Reference Material 8671 NISTmAb
- Collaborative release as a NIST Research Grade Test Material 10197
- MilliporeSigma and the National Institute for Innovation in Manufacturing Biopharmaceuticals (NIIMBL), a Manufacturing USA institute sponsored by NIST, collaborated with NIST to develop NISTCHO
Summary
An industrially-relevant, open-access cell line. NISTCHO meets a need for an open-access mAb-producing cell line that any researcher can obtain. NISTCHO expands the biomanufacturing and research applications of highly-successful NIST Reference Material 8671 NISTmAb. Since its release in 2016, NISTmAb has become a ubiquitous tool for studying mAb proteins in fundamental research, manufacturing development, and quality analysis settings. NISTCHO was originally released as RM 10197 from January 2023 until October 2024.